A Case Study in Model-driven Synthetic Biology

نویسندگان

  • David R. Gilbert
  • Monika Heiner
  • Susan Rosser
  • Rachael Fulton
  • Xu Gu
  • Maciej Trybilo
چکیده

We report on a case study in synthetic biology, demonstrating the modeldriven design of a self-powering electrochemical biosensor. An essential result of the design process is a general template of a biosensor, which can be instantiated to be adapted to specific pollutants. This template represents a gene expression network extended by metabolic activity. We illustrate the model-based analysis of this template using qualitative, stochastic and continuous Petri nets and related analysis techniques, contributing to a reliable and robust design.

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تاریخ انتشار 2008